Author/Authors :
Tahir، نويسنده , , Muhammad Nazir and Qamar، نويسنده , , Riaz-ul and Adnan، نويسنده , , Ahmad and Cho، نويسنده , , Eunae and Jung، نويسنده , , Seunho، نويسنده ,
Abstract :
A micro-reactor based on glass micro-chip functionalized with β-cyclodextrin was prepared and used to develop a flow process for click reactions of aromatic azides and acetylenes. Products with 97–99% yield were obtained within a few minutes. Modified surface remained stable and almost no degradation was observed after 50 h of continuous use.
Keywords :
?-Cyclodextrin , Glass micro-chip , Click reaction , Continuous process
