Title of article
An unusual diepoxyguaianolide from Stevia tomentosa
Author/Authors
Valdez-Calderَn، نويسنده , , Alejandro and Torres-Valencia، نويسنده , , J. Martيn and Manrيquez-Torres، نويسنده , , J. Jesْs and Velلzquez-Jiménez، نويسنده , , René and Romلn-Marيn، نويسنده , , Luisa U. and Hernلndez-Hernلndez، نويسنده , , Juan D. and Cerda-Garcيa-Rojas، نويسنده , , Carlos M. and Joseph-Nathan، نويسنده , , Pedro، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
3286
To page
3289
Abstract
The aerial parts of Stevia tomentosa afforded a new guaianolide which was characterized by physical and spectroscopic data as (−)-1,5:3,4-diepoxyguaia-10(14)-en-12,8-olide (1). The absolute configuration of this unusual compound containing two β-oriented epoxide groups in the five-membered carbocyclic ring, one located at the C-1 and C-5 ring junction, was established as (1S,3S,4S,5R,7R,8R,11S)-1 by vibrational circular dichroism spectroscopy in combination with density functional theory calculations, and by evaluation of Flack and Hooft X-ray parameters.
Keywords
1 , 5:3 , vibrational circular dichroism , 4-Diepoxyguaianolide , X-ray diffraction , absolute configuration
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884736
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