Title of article
Synthesis of alkyl N-(4-nitrophenyl)-3/2-oxomorpholine-2/3-carboxylates by rhodium(II) acetate catalyzed O–H and N–H carbene insertion
Author/Authors
Trstenjak، نويسنده , , Uro? and Ila?، نويسنده , , Janez and Kikelj، نويسنده , , Danijel، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
3341
To page
3343
Abstract
The synthesis of methyl N-(4-nitrophenyl)-3-oxomorpholine-2-carboxylate and ethyl N-(4-nitrophenyl)-2-oxomorpholine-3-carboxylate, via rhodium(II) acetate catalyzed intermolecular O–H and intramolecular N–H carbene insertion, is described. The products represent new and versatile building blocks for the synthesis of bioactive compounds of pharmaceutical interest.
Keywords
Morpholin-2-one , ?-Diazocarbonyl compounds , Morpholin-3-one , Rh2(OAc)4 catalysis , Diazotization
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884760
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