Title of article
Organocatalytic asymmetric Michael addition of 2-naphthols to alkylideneindolenines generated in situ from arenesulfonylalkylindoles
Author/Authors
Yu، نويسنده , , Liangliang and Xie، نويسنده , , Xiaohua and Wu، نويسنده , , Song and Wang، نويسنده , , Rongming and He، نويسنده , , Wujun and Qin، نويسنده , , Dabin and Liu، نويسنده , , Quanzhong and Jing، نويسنده , , Linhai، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
3675
To page
3678
Abstract
An efficient enantioselective Michael addition of 2-naphthols to alkylideneindolenines generated in situ from arenesulfonylalkylindoles has been described. The protocol provides an efficient and convenient access to C-3 alkyl-substituted indole derivatives containing phenolic hydroxyl groups with high yields (up to 96%) and enantioselectivities (up to 98% ee) under mild conditions.
Keywords
organocatalysis , Michael addition , asymmetric synthesis , Arenesulfonylalkylindole , 2-Naphthol
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884902
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