Title of article :
Highly enantioselective conjugate addition of nitroalkanes to enones catalyzed by cinchona alkaloid derived primary amine
Author/Authors :
Liu، نويسنده , , Wenjing and Mei، نويسنده , , Desheng and Wang، نويسنده , , Wei and Duan، نويسنده , , Wenhu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A cinchona alkaloid derived primary amine catalyzed conjugate addition of nitroalkanes to enones is described. The process affords the Michael adducts in good yield and with up to 99% ee for both acyclic and cyclic enones.
Keywords :
enones , Cinchona alkaloids , Chiral primary amine catalysis , Nitroalkanes , asymmetric conjugate addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters