Title of article
Biomimetic hydrogenation: a reusable NADH co-enzyme model for hydrogenation of α,β-epoxy ketones and 1,2-diketones
Author/Authors
Huang، نويسنده , , Qiang and Wu، نويسنده , , Jiwei and Xu، نويسنده , , Hua-Jian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
3877
To page
3881
Abstract
A biomimetic method has been developed to transform α,β-epoxy ketones or 1,2-diketones into corresponding β-hydroxy ketones or α-hydroxy ketones using a catalytic amount of BNAH or BNA+Br−. The regeneration of BNAH or BNA+Br− is achieved by a mixture of HCOOH/Et3N. A radical mechanism is proposed to explain these observations.
Keywords
Biomimetic hydrogenation , ?-Epoxy ketones , 1 , NADH coenzyme model , 2-diketones , ?
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1884985
Link To Document