Author/Authors :
Tanaka، نويسنده , , Naonobu and Momose، نويسنده , , Rei and Takahashi، نويسنده , , Yohei and Kubota، نويسنده , , Takaaki and Takahashi-Nakaguchi، نويسنده , , Azusa and Gonoi، نويسنده , , Tohru and Fromont، نويسنده , , Jane and Kobayashi، نويسنده , , Jun’ichi، نويسنده ,
Abstract :
Two new alkaloids, hyrtimomines D (1) and E (2), were isolated from an Okinawan marine sponge Hyrtios sp. The structures of 1 and 2 were elucidated on the basis of spectroscopic analysis. Hyrtimomines D (1) and E (2) are structurally unique bisindole alkaloids possessing the canthin-6-one skeleton with a hydroxyindole and an imidazolium units. Hyrtimomines D (1) and E (2) exhibited antimicrobial activity.
Keywords :
Hyrtimomines D and E , Hyrtios sp. , Bisindole alkaloids , Marine sponge
