Title of article
Synthesis of β-(trifluoromethyl)furans and spiro-gem-dichlorocyclopropanes from cyclic 1,3-dicarbonyl compounds and α-(trihaloethylidene)nitroethanes
Author/Authors
Barkov، نويسنده , , Alexey Yu. and Korotaev، نويسنده , , Vladislav Yu. and Sosnovskikh، نويسنده , , Vyacheslav Ya.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4181
To page
4184
Abstract
While 1,3-dicarbonyl compounds react with (E)-1,1,1-trifluoro-3-nitrobut-2-ene in the presence of sodium acetate to produce the target β-(trifluoromethyl)furans, their reaction with (E)-1,1,1-trichloro-3-nitrobut-2-ene, under the same conditions, took an entirely different course and gave spiro-gem-dichlorocyclopropanes bearing a 1-nitroethyl moiety, with high diastereoselectivity and in good yields.
Keywords
?-(Trihaloethylidene)nitroethanes , ?-(Trifluoromethyl)furans , 1 , 3-Dicarbonyl compounds , Michael addition , Spiro-cyclopropanation
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885113
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