Title of article
Preparation and palladium-mediated cross-coupling of α-benzoyloxyalkylzinc bromides
Author/Authors
Sakata، نويسنده , , Komei and Urabe، نويسنده , , Daisuke and Inoue، نويسنده , , Masayuki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4189
To page
4192
Abstract
Here we report a two-step preparation protocol of α-benzoyloxyalkylzinc bromides from α-benzoyloxyalkyl selenides, and their application to palladium-catalyzed cross-coupling reactions with aryl and vinyl iodides. The developed method effectively provides a variety of benzoyl-protected benzylic and allylic alcohol derivatives through the formation of C(sp3)–C(sp2) bonds without affecting various polar functional groups.
Keywords
Transition metals , cross-coupling , Synthetic methods , Metalation , organozinc compounds
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885116
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