Title of article
Improved synthesis of N1-substituted orotic acid derivatives
Author/Authors
Senger، نويسنده , , Nicholas A. and Bowler، نويسنده , , Jeannette T. and Mercado، نويسنده , , Rene S. and Lin، نويسنده , , Sidney and Wu، نويسنده , , Weiming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
2
From page
4245
To page
4246
Abstract
An improved method for the synthesis of N1-substituted orotic acid derivatives is reported. The method involves sequential incorporation of nitrogen atoms to the pyrimidine structure from simple starting materials and thus allows the synthesis of N1-substituted orotic acid derivatives with single 15N label at either N-1 or N-3.
Keywords
orotic acid , 1-Substituted orotic acid , Orotidine , 1-Substituted uracil , Dihydrouracil , 5-Bromouracil
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885141
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