Title of article
Use of tridentate TsDPEN/pyridine ligands in ruthenium-catalysed asymmetric reduction of ketones
Author/Authors
Darwish، نويسنده , , Moftah O. and Wallace، نويسنده , , Alistair and Clarkson، نويسنده , , Guy J. and Wills، نويسنده , , Martin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
4250
To page
4253
Abstract
A series of enantiomerically pure tridentate ligands based on the 1,2-diphenylethane-1,2-diamine structure, containing additional pyridine groups, was prepared and tested in asymmetric transfer hydrogenation of ketones using Ru3(CO)12 as a metal source. Alcohols were formed in up to 93% ee in the best cases, and good results were obtained with ortho-haloarylketones.
Keywords
Reduction , Transfer hydrogenation , Ruthenium , alcohol , Asymmetric catalysis
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885143
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