Title of article :
Organocatalytic asymmetric sulfa-Michael addition of thiols to trans-3,3,3-trifluoropropenyl phenyl sulfone
Author/Authors :
Fang، نويسنده , , Xin and Dong، نويسنده , , Xiuqin and Liu، نويسنده , , Yuan-Yuan and Wang، نويسنده , , Chun-Jiang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The first asymmetric sulfa-Michael addition of thiols to trans-3,3,3-trifluoropropenyl phenyl sulfone for the construction of a unique stereogenic center bearing a trifluoromethyl group and a sulfur atom has been achieved in high yields and moderate to good enantioselectivities with 1 mol % bifunctional amine–thiourea catalyst.
Keywords :
Asymmetric catalysis , Amine–thiourea catalyst , Sulfa-Michael addition , Trans-3 , 3-Trifluoropropenyl phenyl sulfone , 3 , Trifluoromethyl group
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
