Title of article
Organocatalytic aldol reaction of indole-3-carbaldehydes with ketones: synthesis of chiral 3-substituted indoles
Author/Authors
Guo، نويسنده , , Qi-Xiang and Wen، نويسنده , , Wei and Fu، نويسنده , , Li-Na and Zhang، نويسنده , , Shun-En and Zhang، نويسنده , , Lan-Xi and Liu، نويسنده , , Yu-Wan and Xu، نويسنده , , Biao and Xiong، نويسنده , , Yan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
4653
To page
4655
Abstract
An efficient aldol reaction of indole-3-carbaldehydes with ketones is described. O-TBS-protected l-threonine promoted the aldol addition of ketones to indole-3-carbaldehydes affording 3-indolylmethanols with good to excellent yields and diastereoselectivities, and excellent enantioselectivities.
Keywords
asymmetric synthesis , Indolylmethanol , organocatalysis , 3-Substituted indole , aldol reaction
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885317
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