Author/Authors :
Zhao، نويسنده , , Bingxin and Wang، نويسنده , , Ying and Li، نويسنده , , Chen and Wang، نويسنده , , Guo-Cai and Huang، نويسنده , , Xiaojun and Fan، نويسنده , , Chunlin and Li، نويسنده , , Qing-Ming and Zhu، نويسنده , , Huajie and Chen، نويسنده , , Wei-Min and Ye، نويسنده , , Wen-Cai، نويسنده ,
Abstract :
Flueggedine (1), a highly symmetrical [2+2] cycloaddition indolizidine alkaloid dimer, was isolated from the twigs and leaves of Flueggea virosa. Its structure with absolute configuration was elucidated by means of NMR and quantum approaches. The plausible biogenetic pathway of 1 was also proposed, which was further supported by biomimetic synthesis.