Title of article
Leucotrichoic acid, a novel sesquiterpene from Sinningia leucotricha (Gesneriaceae)
Author/Authors
Verdan، نويسنده , , Maria Helena and Unemoto، نويسنده , , Lilian K. and Faria، نويسنده , , Ricardo T. and Salvador، نويسنده , , Marcos José and de Sل، نويسنده , , Eduardo Lemos and Barison، نويسنده , , Andersson and Stefanello، نويسنده , , Maria Elida A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
4735
To page
4737
Abstract
Chemical investigation of Sinningia leucotricha (Gesneriaceae) resulted in the isolation of leucotrichoic acid, a sesquiterpene with a novel triquinane skeleton, and the known triterpenes hederagenin and 23-hydroxyursolic acid. The chemical structures of all compounds were elucidated through spectroscopic analysis (NMR and MS). The conformational stability of the new compound was analyzed by density theory functional methods. A possible biogenesis for the new compound is proposed. Leucotrichoic acid was inactive against a panel of human cancer cell lines.
Keywords
Sinningia , Gesneriaceae , Triquinane , NMR , sesquiterpene
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885342
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