Total synthesis of (±)-debromoflustramine B via [4+1] cyclization of a bis(alkylthio)carbene and an indole isocyanate

An efficient total synthesis of (±)-debromoflustramine B and (±)-debromoflustramide B has been achieved, through a novel [4+1] cyclization of an indole isocyanate and bis(alkylthio)carbene.