Title of article :
A modular synthesis of novel 4-amino-7,8-dihydro-1,6-naphthyridin-5(6H)-ones as PDE4 inhibitors
Author/Authors :
Ferrer، نويسنده , , Manel and Roberts، نويسنده , , Richard S. and Sevilla، نويسنده , , Sara، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A versatile, modular synthetic route to a series of 4-amino-7,8-dihydro-1,6-naphthyridin-5(6H)-ones has been developed. These compounds represent a novel structural class of potent phosphodiesterase IV (PDE4) inhibitors.
Keywords :
Modular synthesis , Dihydronaphthyridinone , Tetra-substituted , Inhibitor , PDE4
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters