Title of article :
Synthesis of novel 2H,8H-pyrano[2,3-f]chromene-2,8-diones from 8-formyl-7-hydroxy-4-methylcoumarin
Author/Authors :
Al-Kawkabani، نويسنده , , Ahmed and Boutemeur-Kheddis، نويسنده , , Baya and Makhloufi-Chebli، نويسنده , , Malika and Hamdi، نويسنده , , Maamar and Talhi، نويسنده , , Oualid and Silva، نويسنده , , Artur M.S.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
We report the synthesis of novel 2H,8H-pyrano[2,3-f]chromene-2,8-dione based scaffolds by the reaction of 8-formyl-7-hydroxy-4-methylcoumarin with various active methylene compounds. A mechanism of a tandem Knoevenagel condensation and cyclisation reaction is proposed. The structure of all compounds was established on the basis of 1H and 13C NMR data, high resolution mass spectrometry and elemental analysis.
Keywords :
Coumarin , pyran-2-one , Knoevenagel reaction , Formylation , heterocyclisation , Translactonisation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
