Title of article
Selective deprotection of TBDMS alkyl ethers in the presence of TIPS or TBDPS phenyl ethers by catalytic CuSO4·5H2O in methanol
Author/Authors
Carlos and Gonzلlez-Calderَn، نويسنده , , Davir and Benيtez-Puebla، نويسنده , , Luis J. and Gonzلlez-Gonzلlez، نويسنده , , Carlos A. and Assad-Hernلndez، نويسنده , , Salomَn and Fuentes-Benيtez، نويسنده , , Aydeé and Cuevas-Yلٌez، نويسنده , , Erick and Corona-Becerril، نويسنده , , David and Gonzلlez-Romero، نويسنده , , Carlos، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
5130
To page
5132
Abstract
TBDMS alkyl ethers are efficiently cleaved to the corresponding hydroxyl compounds upon heating (conventional or microwave) in methanol solution containing 20 mol % CuSO4·5H2O. Intramolecular chemoselective experiments showed that TBDMS alkyl ethers are selectively cleaved in the presence of TIPS or TBDPS aryl ethers. Competition experiments also showed that TBDMS alkyl ethers were selectively cleaved in the presence of TBDPS alkyl ethers.
Keywords
alcohols , Silyl ethers , Deprotection , protective groups , Cupric sulfate pentahydrate
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885513
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