Title of article
Monoelectronic reduction of dihydroartemsisinin (DHA): pH dependence and product analysis
Author/Authors
Navacchia، نويسنده , , Maria Luisa and Capobianco، نويسنده , , Massimo L. and D’Angelantonio، نويسنده , , Mila and Marconi، نويسنده , , Giancarlo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
5257
To page
5260
Abstract
The reaction of dihydroartemisinin (DHA) with solvated electrons ( e solv - ) generated under radiolytic conditions showed high pH dependence. The reduction performed under neutral conditions led to the formation of compound P1 deriving from the initial alkoxyl radical as the only detectable product.
Keywords
?-radiolysis , Reduction , malaria , Dihydroartemisinin , alkoxyl radicals
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1885574
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