Title of article :
Monoelectronic reduction of dihydroartemsisinin (DHA): pH dependence and product analysis
Author/Authors :
Navacchia، نويسنده , , Maria Luisa and Capobianco، نويسنده , , Massimo L. and D’Angelantonio، نويسنده , , Mila and Marconi، نويسنده , , Giancarlo، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The reaction of dihydroartemisinin (DHA) with solvated electrons ( e solv - ) generated under radiolytic conditions showed high pH dependence. The reduction performed under neutral conditions led to the formation of compound P1 deriving from the initial alkoxyl radical as the only detectable product.
Keywords :
?-radiolysis , Reduction , malaria , Dihydroartemisinin , alkoxyl radicals
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
