Title of article :
Facile four-component domino reactions for the synthesis of highly functionalized tetrahydroquinolones
Author/Authors :
Muthusaravanan، نويسنده , , Sivasubramanian and Devi Bala، نويسنده , , Balasubramanian and Perumal، نويسنده , , Subbu، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The four-component domino reactions of (E)-3-(dimethylamino)-1-arylprop-2-en-1-ones with anilines, aromatic aldehydes, and 1,3-cyclohexanediones in an equimolar ratio in acetic acid afforded functionalized tetrahydroquinolones in good yields. This one-pot transformation involves the formation of two C–C and two C–N bonds in a single synthetic operation.
Keywords :
Domino reaction , (E)-3-(Dimethylamino)-1-arylprop-2-en-1-one , Aniline , Tetrahydroquinolinones , Four-component
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
