Title of article :
An efficient one-pot synthesis of functionally diverse 2-aminothiazoles from isothiocyanates, amidines/guanidines and halomethylenes
Author/Authors :
Jalani، نويسنده , , Hitesh B. and Pandya، نويسنده , , Amit N. and Pandya، نويسنده , , Dhaivat H. and Sharma، نويسنده , , Jayesh A. and Sudarsanam، نويسنده , , V. and Vasu، نويسنده , , Kamala K.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
An efficient one-pot method for the synthesis of 2-aminothiazoles using simple starting materials like isothiocyanates, amidines/guanidines and various halomethylenes is reported. The synthesis of 2-aminothiazoles involves reactions such as nucleophilic addition, S-alkylation and intramolecular nucleophilic substitution in which amines departs as the leaving group.
Keywords :
2-aminothiazoles , Isothiocyanates , Amidines , Guanidines , one-pot reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
