Author/Authors :
Goudarzi، Hossein نويسنده Shahid Beheshti University of Medical Sciences , , Bandehpour، Mojgan نويسنده , , Eslami، Gita نويسنده , , Fallah، Fatemeh نويسنده , , Heidari، Mohammad نويسنده Department of Microbiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Heidari, Mohammad , Taheri، Sudabeh نويسنده Department of Microbiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Taheri, Sudabeh , Khani Pourroshan، Roxana نويسنده Department of Microbiology, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Khani Pourroshan, Roxana , Momen Heravi، Mansoureh نويسنده , , Khanbanpoor، Mahmood نويسنده Department of Infectious Diseases, Kashan University of Medical Sciences, Kashan, Iran Khanbanpoor, Mahmood
Abstract :
Background: Occurrence of hypersplenism in TB is very rare. We report a case of DTB with hypersplenism
presentation.
Case presentation: A 23year old man was admitted with complaints of fever, night sweats, anorexia, headache,
shortness of breath, early satiety that had started 10 days ago. He had been well until 9 months ago, when early satiety
developed for the first time. Physical and ultrasonographic examinations of the abdomen revealed huge splenomegaly.
The Results of his blood tests showed pancytopenia Abdominal CT scan revealed a mild hepatomegaly, huge
splenomegaly, para-aortic, retroperitoneal, and left inguinal lymphadenopathy. Splenectomy was performed. Pathologic
examination of his liver, spleen and lymph node biopsy specimens revealed caseous necrosis and granuloma formation
due to TB. After initiating the anti-tuberculosis treatment, all of his signs and symptoms disappeared. At the present
time, his general condition is good and he has no any problem
Conclusion: Huge splenomegaly and hypersplenism can occur during disseminated tuberculosis. DTB can mimic
lymphoma and it must be considered in differential diagnosis of huge spleen.
