Title of article :
Outbreak of botulism type E associated with eating traditional soup in a family group, Loghman Hakim Hospital, Tehran, Iran
Author/Authors :
Vahdani، Parviz نويسنده , , Yadegarinia، Davood نويسنده Infectious Diseases and Tropical Medicene Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Aminzadeh، Zohreh نويسنده , , Zare Dehabadi، Mahmood نويسنده Infectious Diseases and Tropical Medicine Research Center, Loghman Hakim Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Zare Dehabadi, Mahmood , Eilami، Owrang نويسنده Infectious Diseases and Tropical Medicine Research Center, Loghman Hakim Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran Eilami, Owrang
Abstract :
Background:
Botulism is a neuroparalytic illness caused by clostridium botulinium toxin that is usually transmitted as a
foodborne disease. It is manifested by cranial nerve dysfunction and descending flaccid muscle paralysis.
Patients:
Eleven members of a family developed severe weakness, lethargy and other clinical manifestations compatible
with botulism following the ingestion of traditional soup. Stool, gastric fluid and serum samples were submitted for
toxicological evaluation with standard mouse bioassay, while, only one patient demonstrated type E toxin. All patients
received 3 monovalent antitoxins A, B and E, whilst most of their symptoms improved within 12 hours.
Conclusion:
This study confirmed that prompt administration of antitoxin could prevent progression of the disease and
may be a life-saving approach.
