Author/Authors :
Siroos، Bahaadin نويسنده Resident of Neurology, Imam Khomeini Hospital, Iranian Center of Neurological Research , , Sharify Bahram، Zahra نويسنده Department of Neurology, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, IR Iran Sharify Bahram, Zahra , Ghaem، Omid نويسنده Department of Radiology, Imam Khomeini Hospital, Tehran University of Medical Sciences Tehran, IR Iran Ghaem, Omid , Zia Ziabari، Seyyed Mahdi نويسنده Department of Emergency Medicine, Poursina Hospital, Guilan University of Medical Sciences, Rasht, IR Iran Zia Ziabari, Seyyed Mahdi , Hedayat Yaghoobi، Mojtaba نويسنده Besat Hospital, Hamedan University of Medical Sciences, Hamedan, IR Iran Hedayat Yaghoobi, Mojtaba
Abstract :
Introduction: Rhino-orbito-cerebral mucormycosis is a progressive angioinvasive fungal disorder which almost always complicates
immunocompromised patients. Case presentation: We described a case of fulminant rhino-orbito-cerebral mucormycosis in a 65-year-old woman, who presented with
progressive neurological deficits due to involvement of orbital apex and the central nervous system by local invasion of the left inferior
frontal lobe, retrograde perineural spreading to the brain stem and middle cerebral arteries thrombosis. Discussion: Early diagnosis is mandatory in managing of this life-threatening disorder. Urgent surgical debridement associated with
antifungal agents (amphotericin with posaconazole) is the mainstay of treatment
