Title of article
One-pot three-component synthesis of indole-3-glyoxyl derivatives and indole-3-glyoxyl triazoles
Author/Authors
Stefani، نويسنده , , Hélio A. and Vasconcelos، نويسنده , , Stanley N.S. and Souza، نويسنده , , Frederico B. and Manarin، نويسنده , , Flلvia and Zukerman-Schpector، نويسنده , , Julio، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
5821
To page
5825
Abstract
A general and efficient reaction of indole with oxalyl chloride and nucleophiles providing indole-3-glyoxyl derivatives has been developed in mild conditions. In the same fashion, the other reaction involved the addition of organic azides leading to the synthesis of indole-3-glyoxyl-1,2,3-triazoles, which proceeds smoothly generating the products in moderate to high yields.
Keywords
indole , Oxalyl chloride , Triazole , Multicomponent reactions (MCRs) , nucleophiles
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886375
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