Author/Authors :
Sato، نويسنده , , Kazuyuki and Isoda، نويسنده , , Motoyuki and Tokura، نويسنده , , Yoriko and Omura، نويسنده , , Keiko and Tarui، نويسنده , , Atsushi and Omote، نويسنده , , Masaaki and Kumadaki، نويسنده , , Itsumaro and Ando، نويسنده , , Akira، نويسنده ,
Abstract :
The reaction of RhCl(PPh3)3 with Et2Zn easily generated a rhodium–hydride complex (Rh−H) that added to α,β-unsaturated esters to form rhodium enolate complexes by formal 1,4-reduction. These rhodium enolates gave the corresponding Reformatsky-type reagents through transmetalation, and they reacted with various aldehydes and ketones to give reductive aldol-type products in good to excellent yields.
Keywords :
Reductive aldol reaction , Diethyl zinc , RhCl(PPh3)3 , Reformatsky–Honda reaction , Rh–H complex
