Title of article
RGD-conjugated triarylmethyl radical as probe for electron paramagnetic imaging
Author/Authors
Patrice Driesschaert، نويسنده , , Benoît and Levêque، نويسنده , , Philippe and Gallez، نويسنده , , Bernard and Marchand-Brynaert، نويسنده , , Jacqueline، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
5924
To page
5926
Abstract
A stable RGD-conjugated triarylmethyl (TAM) radical 3 has been synthesized in a straightforward three-step sequence. CT-03 ‘the Finland trityl’ which is a very popular contrast agent for electron paramagnetic resonance imaging has been covalently bound to the NH2-ending of a pentapeptide commonly used to target integrins and confers tissue selectivity. Moreover, this new TAM radical is stable and sensitive to molecular oxygen.
Keywords
EPR , Trityl radical , RGD , Oximetry
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886423
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