Title of article :
Stereoselective synthesis of (S)-dapoxetine: a chiral auxiliary mediated approach
Author/Authors :
Khatik، نويسنده , , Gopal L. and Sharma، نويسنده , , Ratnesh and Kumar، نويسنده , , Varun and Chouhan، نويسنده , , Mangilal and Nair، نويسنده , , Vipin A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Pages :
3
From page :
5991
To page :
5993
Abstract :
An imidazolidin-2-one chiral auxiliary mediated acetate aldol reaction was explored in the enantioselective synthesis of (S)-dapoxetine (SSRI). The diastereoselective aldol adduct was transformed to highly enantiopure (S)-dapoxetine with overall good yield.
Keywords :
Asymmetric reaction , Acetate aldol , Dapoxetine , chiral auxiliary
Journal title :
Tetrahedron Letters
Serial Year :
2013
Journal title :
Tetrahedron Letters
Record number :
1886452
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1886452
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