Title of article :
Recyclable cinchona alkaloid catalyzed asymmetric Michael addition reaction
Author/Authors :
Huang، نويسنده , , Xin and Yi، نويسنده , , Wen-Bin and Ahad، نويسنده , , Danash and Zhang، نويسنده , , Wei، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A highly enantioselective and diastereoselective Michael addition reaction of α-fluoro-β-ketoesters with maleimides is catalyzed by fluorous cinchona alkaloid to afford two adjacent chiral centers. The catalyst attached with a perfluroalkyl tag can be recovered by fluorous solid-phase extraction (F-SPE).
Keywords :
asymmetric synthesis , organocatalysis , fluorous , Cinchona alkaloid , Michael addition
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
