Author/Authors :
Jenifer Vijay، نويسنده , , T.A. and Nandeesh، نويسنده , , Kebbahalli N. and Raghavendra، نويسنده , , Goravanahalli M. and Rangappa، نويسنده , , Kanchugarakoppal S. and Mantelingu، نويسنده , , Kempegowda، نويسنده ,
Abstract :
A convenient one-pot method for the synthesis of thiochromen-4-ones by the condensation of 2′-haloacetophenone and dithioesters at room temperature in the presence of NaH in DMF in moderate to good yields has been developed. The method involves unusual intramolecular S-arylation. The reaction is operationally facile, readily scalable and offers rapid entry into substituted chromene-4-ones.
Keywords :
Thiochromen-4-ones , Thioflavonones , Dithioesters , Ullman-type intramolecular S-arylation
