Title of article :
Synthesis of γ-lactams via a domino Michael addition/cyclization reaction of vinyl selenone with substituted amides
Author/Authors :
Silvia Sternativo، نويسنده , , Silvia and Battistelli، نويسنده , , Benedetta and Bagnoli، نويسنده , , Luana and Santi، نويسنده , , Claudio and Testaferri، نويسنده , , Lorenzo and Marini، نويسنده , , Francesca، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A novel, simple, and flexible approach to α,α-disubstituted γ-lactams via a domino Michael addition/cyclization process involving the phenyl vinyl selenone and β-ketoamides, malonylamides, or β-cyanoamides is reported. The reactions proceed in good to excellent yields under mild reaction conditions.
Keywords :
lactams , Vinyl selenones , domino reactions , cyclizations , Michael additions
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
