Title of article :
A novel synthesis of γ-nitro ketones via detrifluoroacetylative Michael addition of 1-trifluoromethyl-1,3-diketones to conjugated nitroalkenes
Author/Authors :
Barkov، نويسنده , , Alexey Yu. and Korotaev، نويسنده , , Vladislav Yu. and Sosnovskikh، نويسنده , , Vyacheslav Ya.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A novel synthesis of γ-nitro ketones via detrifluoroacetylative Michael addition of 1-trifluoromethyl-1,3-diketones to conjugated nitroalkenes in the presence of sodium acetate in ethanol at room temperature is developed. A series of trifluoromethylated 1,3-diones and nitroalkenes are surveyed to determine the scope of this high-yielding reaction.
Keywords :
1-Trifluoromethyl-1 , Michael addition , 3-diketones , Nitroalkenes , ?-Nitro ketones , Detrifluoroacetylation
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
