Author/Authors :
Meza-Leَn، نويسنده , , Rosa-L. and Dلvila-Garcيa، نويسنده , , Alvaro and Sartillo-Piscil، نويسنده , , Fernando and Quintero، نويسنده , , Leticia and Rivadeneyra، نويسنده , , Martha Sosa and Cruz-Gregorio، نويسنده , , Silvano، نويسنده ,
Abstract :
A two-step synthesis of naturally occurring alkaloids calyxamines A and B featuring a tandem Mannich–aldol condensation reaction under solvent free conditions, and their inhibitory activity against acetylcholinesterase (AChE) is reported.
Keywords :
organocatalysis , piperidines , Amines , enzymes , aldol reaction