Author/Authors :
Li، نويسنده , , Gang and Wang، نويسنده , , Jin and Yuan، نويسنده , , Baokun and Zhang، نويسنده , , Dongfeng and Lin، نويسنده , , Ziyun and Li، نويسنده , , Peng and Huang، نويسنده , , Haihong، نويسنده ,
Abstract :
The iron-catalyzed heterocyclizations from 2-nitroanilines and benzylic alcohols to form benzimidazoles using hydrogen transfer reaction were investigated in this study. In the presence of dppf in toluene at 150 °C, various benzimidazoles were obtained in moderate to good yields within 24 h. The reaction was proposed to proceed via a cascade of alcohol oxidation, nitro reduction, condensation, and dehydrogenation.
Keywords :
Benzimidazole , Hydrogen transfer , dppf , one-pot synthesis
