Title of article
Sodium carbonate mediated regioselective synthesis of novel N-(hydroxyalkyl)cinnamamides
Author/Authors
Garg، نويسنده , , Parul and Milton، نويسنده , , Marilyn Daisy، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
7074
To page
7077
Abstract
A synthetic protocol for the direct synthesis of N-(hydroxyalkyl)cinnamamides from cinnamates and aminoalcohols in the presence of sodium carbonate as the base is presented. A wide variety of N-(hydroxyalkyl)cinnamamides were isolated in up to 99% yields. The reaction is highly regioselective and yields only N-acylated products by 1,2-addition of aminoalcohols to cinnamates.
Keywords
Regioselective 1 , 2-addition , N-(Hydroxyalkyl)cinnamamides , Cinnamates , Aminoalcohols
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1887032
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