Title of article :
Three-component diastereoselective cascade synthesis of thiohydantoins
Author/Authors :
Ceban، نويسنده , , Victor and Hands، نويسنده , , Kane and Meazza، نويسنده , , Marta and Light، نويسنده , , Mark E. and Rios، نويسنده , , Ramon، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A new three-component cascade reaction for the synthesis of thiohydantoins is reported. The reaction between α-amino esters, nitrostyrenes, and aromatic isothiocyanates is efficiently promoted by organic bases to afford highly substituted thiohydantoins in moderate to good yields and diastereoselectivities.
Keywords :
organocatalysis , cascade reactions , Thiohydantoins , Edman degradation , diastereoselective
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
