Title of article
Bistabercarpamines A and B, first vobasinyl-chippiine-type bisindole alkaloid from Tabernaemontana corymbosa
Author/Authors
Ma، نويسنده , , Ke and Wang، نويسنده , , Jun-Song and Luo، نويسنده , , Jun and Yang، نويسنده , , Ming-Hua and Yao، نويسنده , , He-Quan and Sun، نويسنده , , Hong-Bin and Kong، نويسنده , , Ling-Yi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
101
To page
104
Abstract
Two novel dimeric monoterpene indole alkaloids, bistabercarpamines A (1) and B (2) possessing unprecedented bis-vobasinyl-chippiine-type skeleton, were isolated from the leaves of Tabernaemontana corymbosa. The structures were elucidated on the basis of spectroscopic data, and the absolute configurations of these isolates were determined by CD excition chirality method. Bistabercarpamine A (1) exhibited moderate cell growth inhibitory activity against HepG-2 cells with IC50 of 38.14 ± 1.1 μM.
Keywords
Vobasinyl-chippiine-type bisindole alkaloid , cytotoxic activity , Bistabercarpamines A and B , Tabernaemontana corymbosa
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887134
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