Title of article :
1,1′-Carbonyldiimidazole mediates the synthesis of N-substituted imidazole derivatives from Morita–Baylis–Hillman adducts
Author/Authors :
Rodrigues Jr.، نويسنده , , Manoel T. and Santos، نويسنده , , Marilia S. and Santos، نويسنده , , Hector Hugo and Coelho، نويسنده , , Fernando، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
In this Letter, we describe a simple and straightforward method for the synthesis of N-substituted imidazole derivatives. 1,1-carbonyldiimidazole mediates the process, which requires no activation group step. We obtained imidazole derivatives in high yields and with short reaction times. To demonstrate the synthetic significance of the aforementioned compounds, we also describe the synthesis of novel ionic liquids from these derivatives.
Keywords :
Imidazole , Michael reaction , diastereoselective , Ionic liquids , Morita–Baylis–Hillman
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters