Title of article :
Formal and total synthesis of (±)-cycloclavine
Author/Authors :
Jabre، نويسنده , , Nitinkumar D. and Watanabe، نويسنده , , Teruki and Brewer، نويسنده , , Matthias، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A ring fragmentation and intramolecular azomethine ylide 1,3-dipolar cycloaddition sequence of reactions was successfully used in the preparation of a known (±)-cycloclavine precursor in good overall yield. Results of efforts to incorporate the tetrasubstituted cyclopropane ring present in cycloclavine are also discussed.
Keywords :
Cycloclavine , natural product synthesis , Ring fragmentation , 1 , 3-dipolar cycloaddition , Ergot alkaloid
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
