Title of article
Development of aqueous oxidative Ugi-type reactions by copper-catalyzed surfactant-promoted C(sp3)–H direct functionalization in water
Author/Authors
Xie، نويسنده , , Chunsong and Han، نويسنده , , Laihong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
240
To page
243
Abstract
Direct assembly of α-amino amides from N-alkyl amines and isocyanides through oxidative Ugi-type reactions in aqueous conditions, has been achieved in a Cu(I)–TBHP–surfactant catalysis system. Various N-alkyl amines and isocyanides could be tolerated in this reaction and furnish α-amino amides in moderate yields.
Keywords
surfactant , Copper catalysis , C–H functionalization , Aqueous oxidative Ugi-type reaction
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887199
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