Title of article
An asymmetric iodolactonization reaction catalyzed by a zinc bis-proline–phenol complex
Author/Authors
Filippova، نويسنده , , Liudmila and Stenstrّm، نويسنده , , Yngve and Hansen، نويسنده , , Trond Vidar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
419
To page
422
Abstract
The intramolecular zinc bis-proline-phenol complex 2a was found to promote enantioselective iodolactonization reactions of both electron-rich and electron-poor 5-aryl-5-hexenoic acids affording δ-iodolactones in good chemical yields with up to 82% enantiomeric excess. The reactions were found to be insensitive to air and moisture, providing an experimentally simple protocol for synthetically useful compounds.
Keywords
asymmetric synthesis , Iodolactonization , ?-Iodolactones , Trost ligand , zinc complex
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887564
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