Title of article
Stereoselective synthesis of revised structure of stagonolide G
Author/Authors
Rajendra Prasad، نويسنده , , K. and Venkanna، نويسنده , , A. and Babu، نويسنده , , K. Suresh and Prasad، نويسنده , , A.R. Balavardhana Rao، نويسنده , , J. Madhusudana Rao، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
616
To page
618
Abstract
A concise total synthesis of the revised structure of stagonolide G has been achieved in 11 steps and with an overall yield of 31.7%. Key reaction sequence includes BAIB/TEMPO mediated tandem oxidation and lactonization, Lindlar’s hydrogenation, regioselective epoxide opening by an in situ generated alkynyl as nucleophile, Sharpless asymmetric dihydroxylation, and Jacobsen kinetic resolution.
Keywords
BAIB/TEMPO oxidation , Lactonization , Jacobsen resolution , sharpless asymmetric dihydroxylation , Regioselective epoxide opening
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887744
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