Title of article
ZnCl2 promoted efficient, one-pot synthesis of 3-arylmethyl and diarylmethyl indoles
Author/Authors
Subramaniapillai، نويسنده , , Selva Ganesan and Ganesan، نويسنده , , Asaithampi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
694
To page
698
Abstract
Anhydrous ZnCl2 mediated convenient, one-pot synthesis of 3-arylmethyl and diarylmethyl indoles was accomplished in good yields. Under reaction condition, in situ formation of kinetically stable bis(indolyl)methane product was identified. Its subsequent conversion to the thermodynamically stable 3-diarylmethyl indole at elevated temperature and pressure was confirmed by carrying out pressure tube reaction with bis(indolyl)methane.
Keywords
Friedel–Crafts reaction , Zinc chloride , Pressure tube reaction , 3-Diarylmethyl indole , multicomponent reaction
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887836
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