Title of article
A novel method for the synthesis of aryl trihalomethyl sulfones and their derivatization: the search for new sulfone fungicides
Author/Authors
Korzy?ski، نويسنده , , Maciej D. and Borys، نويسنده , , Krzysztof M. and Bia?ek، نويسنده , , Justyna and Ochal، نويسنده , , Zbigniew، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
745
To page
748
Abstract
A novel method for the preparation of bioactive aryl trihalomethyl sulfones is reported. An iodination reaction with iodine bromide is applied for the synthesis of difluoroiodomethyl aryl sulfones. A series of difluoroiodomethylsulfonyl group bearing derivatives is afforded, including nitroanilines and benzimidazoles. Biological studies show high fungicidal activity for a number of the synthesized sulfones.
Keywords
Difluoroiodomethyl sulfone , Iodine bromide , SNAr reaction , Sulfone fungicides
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887867
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