Title of article
Generation of 1-(trifluoromethyl)-1,2-dihydroisoquinolines via a silver(I)-catalyzed reaction of 2-alkynylaryl aldimine with trimethyl(trifluoromethyl)silane
Author/Authors
Wang، نويسنده , , Xianbo and Qiu، نويسنده , , Guanyinsheng and Zhang، نويسنده , , Ling and Wu، نويسنده , , Jie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
962
To page
964
Abstract
A silver(I)-catalyzed reaction of 2-alkynylaryl aldimine with trimethyl(trifluoromethyl)silane is reported. This reaction proceeds efficiently under extremely mild conditions to generate 1-(trifluoromethyl)-1,2-dihydroisoquinolines in good yields. A three-component reaction of 2-alkynylbenzaldehyde, amine, with trimethyl(trifluoromethyl)silane is presented as well.
Keywords
2-Alkynylaryl aldimine , Silver hexafluorostiboranuide , Amine , 1-(Trifluoromethyl)-1 , 2-Dihydroisoquinoline , Trimethyl(trifluoromethyl)silane
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888023
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