Title of article
Synthesis of novel 5-oxaprotoberberines as bioisosteres of protoberberines
Author/Authors
Jin، نويسنده , , Yifeng and Khadka، نويسنده , , Daulat Bikram and Yang، نويسنده , , Su Hui and Zhao، نويسنده , , Chao and Cho، نويسنده , , Won-Jea Cho، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
1366
To page
1369
Abstract
5-Oxaprotoberberinones and 5-oxaprotoberberinium were synthesized as bioisosteres of protoberberines. 5-Oxaprotoberberinones were prepared by linking phenol with the isoquinolone ring of 3-phenolisoquinolones by methyleneoxy bridge, while the quaternary 5-oxaprotoberberinium salt was synthesized by reduction and oxidation of the lactam moiety of 5-oxaprotoberberinone.
Keywords
Bioisostere , 5-Oxaprotoberberinium , Protoberberine , 5-Oxaprotberberin-8-one
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888233
Link To Document