Title of article :
Efficient synthesis of diversely substituted pyrimidines by palladium catalyzed Suzuki–Miyaura coupling
Author/Authors :
Georgeen and Faldu، نويسنده , , Viral J. and Talpara، نويسنده , , Pratik K. and Shah، نويسنده , , Viresh H. Rawal، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
An efficient synthesis of 2-aryl/heteroaryl substituted pyrimidinyl ethanones 4(a–t) was developed using a palladium-catalyzed Suzuki–Miyaura coupling reaction strategy. Use of Pd(OAc)2 in the presence of PPh3 and Na2CO3 in 1,4-dioxane solvent was found to be the most effective reaction condition.
Keywords :
Suzuki–Miyaura coupling , palladium catalyst , Triphenylphosphine
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
