Author/Authors :
Rao، نويسنده , , Manam Sreenivasa and Haritha، نويسنده , , Meda and Chandrasekhar، نويسنده , , N. and Basaveswara Rao، نويسنده , , Mandava V. and Pal، نويسنده , , Manojit، نويسنده ,
Abstract :
A greener and practical synthesis of 5-substituted thieno[2,3-c]pyran-7-ones has been achieved via Cu-catalyzed coupling-cyclization of 3-iodothiophene-2-carboxylic acid with terminal alkynes in the presence of K2CO3 in PEG 400 under ultrasound irradiation. A range of thienopyranone derivatives were synthesized by using this inexpensive and Pd- and ligand-free methodology.
Keywords :
Ultrasound , Thienopyranone , PEG , Copper
