Title of article
Facile one-step synthesis of 2,5-diketopiperazines
Author/Authors
Sun، نويسنده , , Xianyu and Rai، نويسنده , , Rachita and MacKerell Jr.، نويسنده , , Alexander D. and Faden، نويسنده , , Alan I. and Xue، نويسنده , , Fengtian، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
1905
To page
1908
Abstract
We report a one-step protocol for the general synthesis of 2,5-diketopiperazines from an Fmoc-protected amino acid and an amino acid ester. The application of the method is highlighted by rapid and efficient preparation of various 2,5-diketopiperazines.
Keywords
Diketopiperazine , Fmoc deprotection , Intramolecular cyclization , Amide formation , neuroprotection
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888588
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